職位描述
Job Description
We are seeking a highly motivated scientist/scientific associate to join our in vivo Cancer Pharmacology and Cancer Translational Research team at China Novartis Institute for Biomedical Research (CNIBR) located in the newly completed state-of-art campus in Zhangjiang, Pudong, Shanghai. The scientist/scientific associate will lead/perform in vivo studies in the characterization and development of novel anti-cancer agents, including both small molecules and biologics. The person will interact with in vitro biology, medicinal chemistry, DMPK and bioinformatics teams to advance oncology agents through the R&D pipeline.
Key responsibilities include:
?Establish and characterize animal tumor models
?Conduct in vivo pharmacology studies to evaluate MTD, PK/PD correlation and efficacy of novel therapeutic agents, as well as investigate their mechanism of action in animal tumor models
?Analyze the results and present research findings to project teams
?keep up-to-date with the literature related to the projects
?Effectively collaborate with multi-disciplinary teams
?Manage out-sourcing projects when needed
?Highly value and fully follow IACUC, IP, ISEC and HSE policies
Qualifications:
?A MS degree with 3+ years of experience, or a BS degree with 5+ years of experience in in vivo cancer pharmacology
?Industrial working experiences, especially the experiences in leading in vivo cancer pharmacology studies is preferred
?Solid hands-on skills in cell culture, cell/tumor implantation, drug administration and tissue sampling
?Expertise in in vivo bioluminescence imaging technique and X-ray irradiator is a plus.
?Experience in development or validation of an animal clinical scoring system is a plus.
?Skilled at small animal surgery is a plus.
?Experience in novel in vivo techniques is a plus.
?Detail-oriented, with excellent organizational and record-keeping skills
?Demonstrate a high level of initiative in troubleshooting experiments
?Capable of working both independently and as part of multidisciplinary teams
?Great communication and presentation skills
?Working proficiency in English
企業介紹
作為諾華全球藥物研發網絡的一部分,諾華(中國)生物醫學研究中心(CNIBR)于2007 年正式投入運營,成為跨國醫藥健康企業在華建立的首家、也是規模最大的綜合性研發中心。通過多年發展,研發中心成為諾華生物醫學研究中心(NIBR)在亞太地區的重要基地,依托自身在新藥研發領域的強大實力,通過各種形式的合作與交流惠及包括韓國、日本、臺灣在內的多個國家和地區的醫藥研發。研發中心扎根上海,旨在通過與本土生命科學研究機構廣泛開展合作,引領區域性創新新藥研發。